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In process manufacturing, finished goods can have expiration times, making it hard to schedule many orders optimally, especially when a process is long or has many steps. There can be max and min wait times for work-in-process, which is especially problematic in front of bottlenecks where time-sensitive goods will compete for priority.
Variable setup times, such as equipment cleaning after a pigment change, or after an allergen ingredient is used, also present scheduling challenges, particularly when multiple orders with different recipes have high priorities or upcoming due dates.